Surfer34 Posted November 24, 2010 Share Posted November 24, 2010 So I am guessing all of us who have experienced a subarachnoid hemorrhage and survived are natually concered about the chances and risk of a bleed re-occuring. My doctor said the chance was "very low" and and it sounds like many people on this board have been told similiar things from their doctors. However, I wanted to research the issue myself and find out the true statistics and evidence. Here is what I came up with. 4 studies with approximately 250 study patients and a average follow up time of 3-5 years have found NO cases of a rebleed. The largest study is by Rinkel et al and their study had 160 patients. Cincinnati Study http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1388255/ http://stroke.ahajournals.org/cgi/content/full/38/4/1222 Austria Study http://www.uptodate.com/patients/content/abstract.do?topicKey=%7EkbxUbGmB8WXqiwH&refNum=12 Japan Study http://www.uptodate.com/patients/content/abstract.do?topicKey=%7EkbxUbGmB8WXqiwH&refNum=30 Mayo Clinic Study short version http://www.mayoclinicproceedings.com/content/73/8/745.short long version http://www.mayoclinicproceedings.com/content/73/8/745.full.pdf+html I was very very encouraged that 4 studies found no cases of rebleeds and were confident enough to conclude that there is NO risk of rebleeding. Then I came across a small study of 21 patients that reported a male subject experienced a rebleed 31 months after his first bleed. This was surprising to me but still put the risk/chance of a rebleed at under 1%. http://jnnp.bmj.com/content/69/1/127.abstract?cited-by=yes&legid=jnnp;69/1/127 Upon further research though I found that the authors of previous studies had reviewed the smaller study and found some issues with it, namely the reported cases of the rebleed. They challenged whether it really happended or could be proved. For those who are interested here is a good back and forth between the two study authors. Short version http://jnnp.bmj.com/content/70/3/419.2?cited-by=yes&legid=jnnp;70/3/419a Long version http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737243/pdf/v070p00419a.pdf In my opinion, after reading these exchanges I believe one can conclude that the authors who claimed to have a patient rebleed certainly did not prove such and it can be concluded that no study has ever found and confirmed a patient with a perimesencephalic bleed and rebleed or even an anuerysmal combination with perimesencepahlic. Link to comment Share on other sites More sharing options...
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